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In a large-scale farm in Jiangxi province with 2000 sows in stock, the author selected 1300 healthy lactating piglets around 2-3 weeks of age. They were divided into 3 groups, labeled as 760 in the test group (Yuan Ke Xin group), 514 in the control 1 group (a domestic genetically engineered subunit circular vaccine) and 510 in the control 2 group (a domestic genetically engineered subunit circular vaccine).
For the experiment trail, while the other feeding standards, the other feeding standards, management procedures, and immune care were carried out according to the daily procedures of the farm. Before the test, the test pigs were marked with ear numbers, weighed, and observed the feed intake, feces and mental condition, etc., while keeping relevant records.
Yuan Ke Xin：1 dose of a genetically engineered subunit vaccine against porcine circovirus type 2, 1 ml/head, at an average age of 14 days.
Control: at an average age of 14 days, 1 dose of a domestic genetically engineered subunit circovirus vaccine, 1 ml/head
Through the tracking statistics, for the lactation stage immunization age, weaning average weight, as well as stress and overall health status to assess; for the nursing stage, mainly for the dead amoy rate, daily weight gain, material to meat ratio for analysis and comparison; the results are as follows.
Table 1 Statistical analysis of lactation stage data
| Group Name | Animal Quantity（head） | Vaccination Age （day-old） | Average Weaning Weight（kg） | Stress Condition | Health Condition |
| Yuan Ke Xin Group | 760 | 14 | 7.75 | None | Healthy |
| Control Group 1 | 514 | 14 | 7.85 | None | Healthy |
| Control Group 2 | 510 | 14 | 7.24 | None | Healthy |
Table 2 Statistical analysis of experimental production data
| Group Name | Animal Quantity（head） | Mortality | Average Weight（kg） | Daily weight Gain（g） | FCR | Average number of days in the test（day） |
| Yuan Ke Xin Group | 758 | 0.2% | 28.42kg | 411g | 1.634:1 | 50 |
| Control Group 1 | 511 | 0.5% | 29.5kg | 441g | 1.665：1 | 49 |
| Control Group 2 | 505 | 1% | 27.9kg | 440g | 1.635；1 | 47 |
From the above clinical application results, it can be seen that.
In terms of immune safety, both round ring vaccines did not show immune stress reactions and both showed good vaccine safety.
In terms of vaccine efficacy, both the YuanKeXin and the domestic genetically engineered subunit round vaccine showed consistent immunization effect in terms of meat ratio and average weight, and were significantly better than the domestic genetically engineered subunit round vaccine in terms of dead panning rate, showing good clinical application effect.
